SANDOZ ACTS 200 tablets 200 mg No. 20

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SANDOZ ACTS 200 tablets 200 mg No. 20
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Adults - For children - For wet coughs - For dry coughs - Expectorants - Tablets
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Characteristics of SANDOZ ACC 200 tablets 200 mg No. 20

Yandex.Market data
General characteristics
Drug type medicinal product
Release form effervescent tablets
Minimum age of use from 2 years
Appointment From cough
Additionally
Indications for use - diseases of the respiratory system, accompanied by the formation of viscous difficult to separate sputum (acute and chronic bronchitis, obstructive bronchitis, tracheitis, laryngotracheitis, pneumonia, lung abscess, bronchiectasis, bronchial asthma, COPD, bronchiolitis, cystic fibrosis);
- acute and chronic sinusitis;
- otitis media.
Contraindications - peptic ulcer of the stomach and duodenum in the acute phase;
- hemoptysis;
- pulmonary bleeding;
- pregnancy;
- lactation period (breastfeeding);
- children up to 14 years old (ACC Long);
- children's age up to 2 years (ACC 200);
- lactase deficiency, lactose intolerance, glucose-galactose malabsorption;
- hypersensitivity to drug components.
The drug should be used with caution in patients with a history of gastric ulcer and duodenal ulcer; with bronchial asthma, obstructive bronchitis; hepatic and / or renal failure; histamine intolerance (long-term use of the drug should be avoided, since acetylcysteine ​​affects the metabolism of histamine and can lead to signs of intolerance, such as headache, vasomotor rhinitis, itching); varicose veins of the esophagus; diseases of the adrenal glands; arterial hypertension.
Active substance Acetylcysteine
Method of administration and dosage The drug is taken orally after meals. Effervescent tablets should be dissolved in 1 glass of water. The tablets should be taken immediately after dissolution, in exceptional cases, you can leave the finished solution for 2 hours. Additional liquid intake enhances the mucolytic effect of the drug.
Adults and adolescents over 14 years of age are recommended to prescribe the drug 200 mg (ACC 200) 2-3 times / day, which corresponds to 400-600 mg of acetylcysteine ​​per day, or 600 mg (ACC Long) 1 time / day.
Children aged 6 to 14 years old are recommended to take 1 tab. (ACC 200) 2 times / day, which corresponds to 400 mg of acetylcysteine ​​per day.
For children aged 2 to 6 years, the drug is recommended to take 1/2 tab. (ACTS 200) 2-3 times / day, which corresponds to 200-300 mg of acetylcysteine ​​per day.
In case of cystic fibrosis, children over the age of 6 years should take the drug 1 tab. (ACTS 200) 3 times / day, which corresponds to 600 mg of acetylcysteine ​​per day. Children aged 2 to 6 years - 1/2 tab. (ACTS 200) 4 times / day, which corresponds to 400 mg of acetylcysteine ​​per day.
For short-term colds, the duration of admission is 5-7 days. In chronic bronchitis and cystic fibrosis, the drug should be used for a longer period to prevent infections.
Side effects According to the WHO, adverse effects are classified according to their frequency of development as follows: very often (≥1 / 10), often (≥1 / 100, <1/10), infrequently (≥1 / 1000, <1/100), rare (≥1 / 10,000, <1/1000), very rare (<10,000), frequency unknown (incidence cannot be determined from available data).
Allergic reactions: infrequently - itching, rash, exanthema, urticaria, angioedema; very rarely - anaphylactic reactions up to shock, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell's syndrome).
From the respiratory system: rarely - shortness of breath, bronchospasm (mainly in patients with bronchial hyperreactivity in bronchial asthma).
From the side of the cardiovascular system: infrequently - lowering blood pressure, tachycardia.
From the digestive system: infrequently - stomatitis, abdominal pain, nausea, vomiting, diarrhea, heartburn, dyspepsia.
From the organ of hearing: infrequently - tinnitus.
Others: infrequently - headache, fever; in isolated cases - the development of bleeding as a manifestation of a hypersensitivity reaction, a decrease in platelet aggregation.
Storage conditions ACTS 200 should be stored out of the reach of children, in a dry place at a temperature not exceeding 25 ° C.
ACC Long should be stored out of the reach of children, in a dry, dark place at a temperature not exceeding 30 ° C.
The shelf life is 3 years.
After taking the pill, the tube should be tightly closed.
Overdose Symptoms: with an erroneous or deliberate overdose, such phenomena as diarrhea, vomiting, stomach pains, heartburn, nausea are observed.
Treatment: symptomatic therapy.
special instructions In bronchial asthma and obstructive bronchitis, acetylcysteine ​​should be prescribed with caution under systematic monitoring of bronchial patency.
With the use of acetylcysteine, cases of severe allergic reactions such as Stevens-Johnson syndrome and Lyell's syndrome have been reported very rarely. If changes occur in the skin and mucous membranes, the patient should immediately stop taking the drug and consult a doctor.
When dissolving the drug, it is necessary to use glassware, avoid contact with metals, rubber, oxygen, easily oxidized substances.
You should not take the drug immediately before bedtime (the preferred time of admission is before 18.00).
1 effervescent tablet ACTS 200 corresponds to 0.006 XE, 1 effervescent tablet ACTS Long - 0.001 XE.
No special precautions are required when disposing of unused ACC effervescent tablets.
Influence on the ability to drive vehicles and use mechanisms
There are no data on the negative effect of the drug on the ability to drive vehicles and mechanisms, when used in recommended doses.
Interaction With the simultaneous use of acetylcysteine ​​and antitussives due to suppression of the cough reflex, sputum stagnation may occur.
With the simultaneous use of acetylcysteine ​​and antibiotics for oral administration (penicillins, tetracyclines, cephalosporins, etc.), the latter may interact with the thiol group of acetylcysteine, which can lead to a decrease in antibacterial activity. Therefore, the interval between taking antibiotics and acetylcysteine ​​should be at least 2 hours (except for cefixime and loracarbef).
Simultaneous use with vasodilators and nitroglycerin can lead to an increase in the vasodilator effect.
pharmachologic effect Mucolytic drug. Acetylcysteine ​​is a derivative of the amino acid cysteine. It has a mucolytic effect, facilitates the discharge of sputum due to a direct effect on the rheological properties of sputum. The action is due to the ability to break the disulfide bonds of mucopolysaccharide chains and cause depolymerization of mucoproteins in sputum, which leads to a decrease in the viscosity of sputum. The drug remains active in the presence of purulent sputum.
It has an antioxidant effect due to the ability of its reactive sulfhydryl groups (SH-groups) to bind to oxidative radicals and thus neutralize them.
In addition, acetylcysteine ​​promotes the synthesis of glutathione, an important component of the antioxidant system and chemical detoxification of the body. The antioxidant effect of acetylcysteine ​​increases the protection of cells against the damaging effects of free radical oxidation inherent in an intense inflammatory response.
With the prophylactic use of acetylcysteine, there is a decrease in the frequency and severity of exacerbations in patients with chronic bronchitis and cystic fibrosis.
Structure 1 tab .: acetylcysteine ​​- 200 mg.
Excipients: anhydrous citric acid - 558.5 mg, sodium bicarbonate - 200 mg, sodium carbonate anhydrous - 100 mg, mannitol - 60 mg, anhydrous lactose - 70 mg, ascorbic acid - 25 mg, sodium saccharinate - 6 mg, sodium citrate - 0.5 mg, blackberry "B" flavor - 20 mg.
Registration number P N015473 / 01
Date of state registration 18.09.2014

Reviews about SANDOZ ACTS 200 tablets 200 mg No. 20

Yandex.Market data
Rating: 5 out of 5
Vladimir Skvortsov
Advantages: Good effervescent tablets. Helps with wet coughs. 3 ACC 200 tablets are approximately equal to 1 ACC LONG. I take ACC 200, as you need to take it during the day and, in my personal opinion, it is better than 1 time per day.
Comment:
January 25, 2020, Moscow
Rating: 4 out of 5
Excellent but too expensive
10 april 2018
Rating: 5 out of 5
Great pills, helps a lot! Do not be ill))
Feb 10, 2017
Rating: 5 out of 5
Great for Macrota and Wet Cough!
15 october 2016
Rating: 5 out of 5
I advise it helps from makrota
2 March 2016
Rating: 5 out of 5
Very good medicine
28 November 2015
Rating: 4 out of 5
Fu doesn't taste good
November 10, 2015
Rating: 5 out of 5
Great product helps pretty quickly
17 october 2015
Rating: 5 out of 5
A very effective remedy !!! Thinns phlegm! It starts acting immediately!
August 27, 2015
Rating: 4 out of 5
An amateur taste. It helps a lot. Cool dissolves ^^
21 Aug 2015

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