Frontline Merial Combo S
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Buy Front Line Merial Combo S
Front Line Merial Combo S Features
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| Appointment | |
| Kind of animal | dogs |
| Animal weight | from 2 to 10 kg |
| Animal age | |
| Release form and packaging | |
| Item type | drops |
| Preparation volume | 0.67 ml |
| Description | |
| Duration of action | 30 days |
| Active substance | fipronil |
| Indications for use | Frontline Combo is used to combat fleas, lice, lice and ticks (ixodid, cheilitella) externally, by topical (Spot On) application to the skin. |
| Pharmacological properties and composition | It has a pronounced contact insectoacaricidal effect, is active against the preimaginal and imaginal phases of development of lice, fleas, lice and ticks (ixodid, cheilitella), parasitizing on dogs. The mechanism of action of fipronil is to block the GABA-dependent (GABA-gamma-aminobutyric acid) receptors of parasites, impairing the transmission of nerve impulses, which leads to paralysis and death of ectoparasites. S-methoprene inhibits the juvenile hormone that promotes the formation of chitin, thereby disrupting the development of fleas at the egg and larval stage. When applied to the skin, the drug is not absorbed, but gradually, within 24 hours, is distributed over the surface of the body and, being reserved in the sebaceous glands, has a long-term insectoacaricidal effect in the places of localization of ectoparasites. |
| Application and dosage | Before processing, the tip of the pipette is broken off, the animal's hair is pushed apart in the back region (between the shoulder blades) and, pressing the pipette, the preparation is applied to the skin at one or several points. The protective effect of the drug against ixodic ticks in cats lasts up to 3 weeks, against the imago and preimaginal phases of insect development up to 6 weeks, in dogs against ixodic ticks the protection is effective for at least 1 month, against imago insects for up to 3 months, from preimaginal phases of insect development up to 8 months. In case of severe damage to the animal by lice, fleas, lice, it is recommended to process it once a month. If the animal is washed more than 2 times a month, it is recommended to reduce the interval between treatments to 3 weeks. It is not recommended to wash animals within 48 hours after treatment with Frontline Combo, as well as to use other insecticidal acaricides. |
| Contraindications and side effects | Side effects: In terms of the degree of impact on the body, Frontline Combo belongs to low-hazard substances (hazard class 4 according to GOST 12.1.007.76), in recommended doses, it does not have a skin-resorptive, sensitizing, embryotoxic, teratogenic and mutagenic effect. Causes slight irritation in eye contact. Contraindications: Increased individual sensitivity to the drug components. Sick and recovering animals, as well as puppies, cannot be processed. |
