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Unique Pharmaceuticals Rinzasip with Vitamin C d / inv. r-ra d / int. taking sachet 5g No. 10

Unique Pharmaceuticals Rinzasip with Vitamin C. d / inv. r-ra d / int. taking sachet 5g No. 10

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For adults - Powders - For ARVI - For colds

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Buy Unique Pharmaceuticals Rinzasip with Vitamin C. d / inv. r-ra d / int. taking sachet 5g No. 10

Characteristics of Unique Pharmaceuticals Rinzasip with Vitamin C. d / inv. r-ra d / int. taking sachet 5g No. 10

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General characteristics
Drug type	medicinal product
Organs and systems	respiratory system
Appointment	feverish conditions, runny nose, acute respiratory infections, acute respiratory viral infections, symptomatic treatment of colds, flu, acute respiratory viral infections, symptomatic therapy of acute respiratory viral infections
Indications for use	- symptomatic treatment of colds, flu, SARS (febrile syndrome, pain syndrome, rhinorrhea).
Contraindications	- the simultaneous administration of other medicines containing substances that make up the drug; - Simultaneous intake of tricyclic antidepressants, MAO inhibitors, beta-blockers; - pregnancy; - lactation period; - children's age (up to 15 years old); - deficiency of sucrase / isomaltase, fructose intolerance, glucose-galactose malabsorption; - hypersensitivity to paracetamol and other components that make up the drug. With caution: severe atherosclerosis of the coronary arteries, arterial hypertension, thyrotoxicosis, pheochromocytoma, diabetes mellitus, bronchial asthma, chronic obstructive pulmonary disease, deficiency of glucose-6-phosphate dehydrogenase, blood diseases, congenital hyperbilirubinemia (Gillonbert's and Dubin's liver syndrome) and / or renal failure, angle-closure glaucoma, prostatic hyperplasia.
Structure	1 sachet (5 g): paracetamol 750 mg, ascorbic acid (vit. C) 200 mg, caffeine 30 mg, pheniramine maleate 20 mg, phenylephrine hydrochloride 10 mg. Excipients: citric acid - 200 mg, sodium saccharinate - 40 mg, sodium citrate - 500 mg, sucrose - 3062.5 mg, sunset yellow dye (E110) - 7.5 mg, orange flavor - 150 mg.
Active substance	Caffeine + Paracetamol + Phenylephrine + Pheniramine + Ascorbic Acid
Method of administration and dosage	Adults and children over 15 years of age are prescribed 1 sachet 3-4 times / day with intervals between doses of 4-6 hours. The maximum daily dose is 4 sachets. The course of treatment without consulting a doctor is no more than 5 days. Before use, the contents of 1 sachet must be poured into a glass, filled with hot water, stirred until completely dissolved and drunk (sugar or honey can be added if desired).
Side effects	Allergic reactions: skin rash, itching, urticaria, angioedema. From the nervous system: dizziness, sleep disturbance, increased excitability. From the side of the cardiovascular system: increased blood pressure, tachycardia. From the digestive system: nausea, vomiting, pain in the epigastric region, dryness of the oral mucosa, hepatotoxic effect. From the senses: mydriasis, paresis of accommodation, increased intraocular pressure. From the side of hematopoiesis: anemia, thrombocytopenia, agranulocytosis, hemolytic anemia, aplastic anemia, methemoglobinemia, pancytopenia. From the urinary system: urinary retention, nephrotoxicity (papillary necrosis). Others: bronchospasm.
pharmachologic effect	The combined preparation has an antipyretic, analgesic, alpha-adrenostimulating, vasoconstrictor and antihistamine effect, eliminates the symptoms of a cold. Paracetamol is a non-narcotic analgesic; blocks cyclooxygenase, mainly in the central nervous system, affecting the centers of pain and thermoregulation; has an analgesic and antipyretic effect. Phenylephrine is an alpha-adrenergic agonist with a moderate vasoconstrictor effect. Reduces edema and hyperemia of the mucous membranes of the upper respiratory tract and paranasal sinuses. Pheniramine is a blocker of H1-histamine receptors. It has an anti-allergic effect: eliminates itching of the eyes, nose and throat, swelling and hyperemia of the mucous membranes of the nasal cavity, nasopharynx and paranasal sinuses, reduces exudative manifestations. Caffeine has a stimulating effect on the central nervous system, enhances the effect of analgesics, eliminates drowsiness and fatigue, increases physical and mental performance, reduces fatigue and drowsiness. Ascorbic acid (vitamin C) is involved in the regulation of redox processes, carbohydrate metabolism, blood clotting, tissue regeneration, in the synthesis of steroid hormones; reduces vascular permeability and increases the body's resistance to the effects of various adverse environmental factors.
Pharmacological group	ARI and "cold" symptoms remedy
Release form	powder for oral solution
Method of application / administration	oral
Minimum age of use	from 15 years
Additionally
Storage conditions	The drug should be stored in a dry place out of the reach of children at a temperature not exceeding 25 ° C. The shelf life is 3 years.
Overdose	Symptoms (mainly due to paracetamol): pallor of the skin, anorexia, nausea, vomiting; hepatonecrosis; increased activity of hepatic transaminases, increased prothrombin time. Treatment: gastric lavage, the appointment of activated carbon, the introduction of methionine (within 8-9 hours after an overdose) and N-acetylcysteine (within 8-9 hours after an overdose), symptomatic therapy.
Application during pregnancy and lactation	The drug is contraindicated in pregnancy and lactation.
Influence on the ability to drive vehicles and mechanisms	During the period of taking the drug, it is necessary to refrain from driving vehicles and engaging in other potentially hazardous activities that require increased concentration of attention and speed of psychomotor reactions.
special instructions	The patient should be warned that in the absence of a therapeutic effect (hyperthermia for more than 3 days and pain syndrome for more than 5 days), you should consult a doctor. The drug contains sucrose, which must be taken into account by patients with diabetes mellitus, as well as patients on a low-calorie diet. 1 single dose of the drug contains from 2915.0 mg to 3136.0 mg of sucrose, which corresponds to 0.24-0.26 XE. The patient should be informed that if the medicinal product has become unusable or the expiration date has expired, then it should not be thrown into the wastewater or on the street. Place the medicine in a bag and put it in the trash can. These measures will help protect the environment.
Interaction	Enhances the effects of MAO inhibitors, sedatives, ethanol. Antidepressants, antiparkinsonian drugs, antipsychotics, phenothiazine derivatives - increase the risk of urinary retention, dry mouth, constipation. Glucocorticosteroids increase the risk of developing glaucoma. Paracetamol reduces the effectiveness of uricosuric drugs. Pheniramine concurrently with MAO inhibitors, furazolidone can lead to hypertensive crisis, agitation, hyperpyrexia. Tricyclic antidepressants increase the adrenomimetic effect of phenylephrine, the simultaneous administration of halothane increases the risk of ventricular arrhythmia. With the simultaneous administration of the drug with barbiturates, phenytoin, carbamazepine, rifampicin and other inducers of liver microsomal enzymes, the risk of developing the hepatotoxic effect of paracetamol increases.
Registration number	LS-002579
Date of state registration	22.09.2014
Marketing Authorization Holder	Johnson & Johnson
Manufacturer	Unique Pharmaceuticals
Packer	Unique Pharmaceuticals
Manufacturer country	India
Drug name	Rinzasip